The negative-feedback loop
Sense deviation β trigger correction β return to set point.
Homeostasis uses negative feedback: when something deviates from the set point, the body triggers a correction in the OPPOSITE direction.
General loop:
- RECEPTOR senses change (e.g. skin temperature drops).
- COORDINATOR (brain or gland) processes the information.
- EFFECTOR responds (muscle shivers, gland releases hormone).
- Result: condition returns toward the set point.
This is similar to a thermostat keeping a room at a fixed temperature β heat off when too warm, on when too cool.
Why 'negative'? Because the response is in the OPPOSITE direction to the disturbance. The feedback corrects, not amplifies.
Body conditions kept by homeostasis:
- Temperature (~37 Β°C).
- Blood glucose (~5 mmol/L).
- Blood pH (~7.4).
- Water + salt balance.
- Blood pressure.
- Receptor β coordinator β effector β return to normal.
- Negative feedback: response opposes the disturbance.
- Maintains T, glucose, pH, water, blood pressure.