Cambridge IGCSE Biology (0610)

IGCSE Biology, in the words examiners want.

Biology marks hang on precise keywords. Your tutor explains each process, drills the terms with you and shows exactly which words earn the marks.

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Explain why the rate of an enzyme-controlled reaction falls at high temperatures.[3 marks]

This is worth 3 marks. They go for:

  • The enzyme is denatured (1 mark)
  • The shape of the active site changes (1 mark)
  • The substrate no longer fits, so fewer enzyme–substrate complexes form (1 mark)

Examiner tip: Write “denatured” and “active site”. “The enzyme dies” or “is killed” earns nothing.

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Assessment

How Cambridge IGCSE Biology is assessed

Core students take Papers 1 and 3 and can get grades C–G. Extended students learn the Core and Supplement content, take Papers 2 and 4, and can get grades A*–G. Everyone also takes Paper 5 or Paper 6.

Syllabus 0610, for exams in 2026–2028.

Core (grades C–G)

  • Paper 1: Multiple Choice (Core)

    40 four-option multiple-choice questions

    Time
    45 min
    Marks
    40
    Weight
    30%
  • Paper 3: Theory (Core)

    Short-answer and structured questions

    Time
    1 h 15 min
    Marks
    80
    Weight
    50%

Extended (grades A*–G)

  • Paper 2: Multiple Choice (Extended)

    40 four-option multiple-choice questions

    Time
    45 min
    Marks
    40
    Weight
    30%
  • Paper 4: Theory (Extended)

    Short-answer and structured questions

    Time
    1 h 15 min
    Marks
    80
    Weight
    50%

Everyone takes one practical paper

  • Paper 5: Practical Test

    Practical test of experimental skills

    Time
    1 h 15 min
    Marks
    40
    Weight
    20%
  • Paper 6: Alternative to Practical

    Written paper on experimental skills

    Time
    1 h
    Marks
    40
    Weight
    20%

Your school chooses Paper 5 (a practical test) or Paper 6 (a written alternative to practical). Either is worth 20%. There is no coursework.

From the official Cambridge International syllabus, checked October 2026. Read the syllabus

Syllabus content

What’s on the Cambridge IGCSE Biology syllabus

  • Characteristics and classification of living organisms
  • Organisation of the organism
  • Movement into and out of cells
  • Biological molecules
  • Enzymes
  • Plant nutrition
  • Human nutrition
  • Transport in plants
  • Transport in animals
  • Diseases and immunity
  • Gas exchange in humans
  • Respiration
  • Excretion in humans
  • Coordination and response
  • Drugs
  • Reproduction
  • Inheritance
  • Variation and selection
  • Organisms and their environment
  • Human influences on ecosystems
  • Biotechnology and genetic modification

Where marks are lost

Common Cambridge IGCSE Biology mistakes

  • “Plants respire at night and photosynthesise in the day.”

    Plants respire all the time, day and night. Photosynthesis only happens in the light.

  • Describing osmosis as diffusion of anything.

    Osmosis is the movement of water molecules through a partially permeable membrane, from a dilute solution to a more concentrated one.

  • Describing a graph without numbers.

    Give the trend, then quote values from the graph with their units. “It increases” on its own rarely gets full marks.

Six biology tutors, six ways to learn

Practise past-paper style questions with the exam coach, drill facts before a test with quick revision, or slow down with a step-by-step tutor. Switch any time.

  • KaiConcept explainer
  • ElenaStep by step
  • SamuelExam coach
  • MayaQuick revision
  • JonahChallenger
  • NiaConfidence builder

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FAQ

Cambridge IGCSE Biology questions, answered.

Tell your tutor which topics feel weakest, or upload a recorded lesson. A quick-revision tutor can quiz you across topics to find the gaps first.

Yes. Send a photo of your diagram and ask your tutor to check the labels, or ask it to quiz you on a diagram from your textbook.

Yes. Tell your tutor you’re taking Extended and it includes the Supplement content.

Yes. The free plan includes 5 tutor messages and 15 minutes of calls a day. Pro and Max give you more when exams get close.

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More Cambridge IGCSE subjects

Biology in other curricula